Glossary Term
Restriction Endonuclease
PCR TermsEN
Definition
Enzymes that exhibit endonuclease activity at a specific short nucleotide sequence to cleave strands of DNA.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16515. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Restriction EndonucleaseRestriction Enzyme
References
- NCI Thesaurus 26.09d — Restriction Endonuclease (C16515)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16515. NCI definition, reproduced without modification under CC BY 4.0.
- Discovery of the first known restriction endonuclease target site in DNA: Enzymes from Hemophilus influenzae. — Gene, 2026-08-14 (PMID 42600669; literature)
- A one-pot detection method based on restriction endonuclease recognition for rapid detection of canine parvovirus and precise genotyping of the 2c variant. — Anal Chim Acta, 2026-06-19 (PMID 42567608; literature)
- Multiple inducible DNA double-strand breaks using a restriction endonuclease in Arabidopsis thaliana mitochondria. — BMC Plant Biol, 2026-06-03 (PMID 42231171; literature)
- Highly sensitive and rapid determination of Coxsackievirus A16 using restriction endonuclease-mediated reverse transcription multiple cross displacement amplification. — BMC Microbiol, 2026-05-25 (PMID 42185971; literature)
- Structure-guided design and rapid cell-free screening of a superior restriction endonuclease DpnI mutant to enhance the specific activity and efficiency of site-directed mutagenesis. — Biosci Biotechnol Biochem, 2026-05-01 (PMID 41848284; literature)