National Cancer Institute (source definition)
Surface Plasmon Resonance
A quantum optical-electrical phenomena consisting of an alteration in light reflectance as a result of binding of molecules to a surface from which total internal reflection is occurring. Used to detect macromolecular interactions, SPR can be used as the basis for a sensor which is capable of sensitive and quantitative measurement of a broad spectrum of chemical and biological entities.
Review and references
Automated source check (NCI definition)
2026-10-20
2026-10-28
professional use
References
- NCI Thesaurus 26.09d — Surface Plasmon Resonance (C18117)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C18117. NCI definition, reproduced without modification under CC BY 4.0.
- A Lateral Flow-Based Whole Blood Sample Preparation for Surface Plasmon Resonance Sensing of Ferritin in Frequent Blood Donors. — ACS Sens, 2026-10-24 (PMID 42925541; literature)
- Optimization of copper and tin disulfide based surface plasmon resonance for the detection of brain tumor tissues. — Discov Nano, 2026-10-22 (PMID 42911311; literature)
- Comparative kinetic analysis of PNA and γ-miniPEG-PNA hybridization with RNA by surface plasmon resonance. — Org Biomol Chem, 2026-10-22 (PMID 42908982; literature)
What it is
A quantum optical-electrical phenomena consisting of an alteration in light reflectance as a result of binding of molecules to a surface from which total internal reflection is occurring. Used to detect macromolecular interactions, SPR can be used as the basis for a sensor which is capable of sensitive and quantitative measurement of a broad spectrum of chemical and biological entities.
Source: National Cancer Institute, NCI Thesaurus 26.09d, C18117. NCI definition, reproduced without modification under CC BY 4.0.
Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Compliance note
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
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