Article
Response to: 'Comment on 'Metagenomic next-generation sequencing: a game changer in the diagnosis of unique intraocular infections''.
Research record from Eye (Lond), 2026-03-27. PMID 41896456.
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Article
Research record from Eye (Lond), 2026-03-27. PMID 41896456.
Glossary Term
Enzymes that exhibit endonuclease activity at a specific short nucleotide sequence to cleave strands of DNA.
Glossary Term
A sequence in DNA that can be recognized by a specific restriction enzyme.
Indicators
The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.
Glossary Term
A study in which participants with known outcomes are assessed based on data collected before the study.
Glossary Term
A two-step setup in which RNA is first copied into complementary DNA by a reverse transcriptase and then amplified by PCR. Used for RNA viruses such as influenza, RSV, SARS-CoV-2, and HCV. In procurement documents, confirm whether "RT-PCR" refers to real-time (quantitative) or endpoint (qualitative) reading.
Article
Research record from BMC Infect Dis, 2026-04-21. PMID 42015023.
Indicators
An essential human nutrient that is a heat-stable and water-soluble flavin belonging to the vitamin B family. Riboflavin is a precursor of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD). These coenzymes are of vital importance in normal tissue respiration, pyridoxine activation, tryptophan to niacin conversion, fat, carbohydrate, and protein metabolism, and glutathione reductase mediated detoxification. Riboflavin may also be involved in maintaining erythrocyte integrity. This vitamin is essential for healthy skin, nails, and hair.
Glossary Term
Ribonuclease inhibitor (461 aa, ~50 kDa) is encoded by the human RNH1 gene. This protein plays a role in the inhibition of ribonucleases.
Tests
A test designed to detect the presence of Rickettsia conorii antibodies in serum.
Indicators
This gene plays a role in receptor tyrosine phosphorylation signal transduction, and is thought to play a role in cellular growth or differentiation, but an exact function has not been substantiated.
Indicators
This gene plays a role in transcriptional regulation and cytogenetic aberrations are associated with several leukemias.