Indicator Explainer
RUNX1 Gene
This gene plays a role in transcriptional regulation and cytogenetic aberrations are associated with several leukemias.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C18579. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — RUNX1 Gene (C18579)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C18579. NCI definition, reproduced without modification under CC BY 4.0.
- [Clinical characteristics and prognosis of acute myeloid leukemia patients with RUNX1 single-site and multiple-site gene mutations]. — Zhonghua Xue Ye Xue Za Zhi, 2026-06-01 (PMID 42706154; literature)
- Efficacy of DMARDs Therapy on the Disease Activity and Gene Expression Levels of FoxO1, FoxO3, Runx1, and Runx3 in Early Rheumatoid Arthritis Patients: A Pre-Post Interventional Study With Healthy Controls. — Health Sci Rep, 2025-10-21 (PMID 41132193; literature)
- t(8;21)(q23;q22), a Novel Translocation Involving the RUNX1 Gene in a Patient with Acute Myeloid Leukemia. — J Assoc Genet Technol, 2025-01-01 (PMID 41452378; literature)
- Enhanced osteogenic potential of iPSC-derived mesenchymal progenitor cells following genome editing of GWAS variants in the RUNX1 gene. — Bone Res, 2024-12-06 (PMID 39643619; literature)