Indicators
A water-soluble vitamin belonging to the vitamin B family, which occurs in many animal and plant tissues, with antihyperlipidemic activity. Niacin is converted to its active form niacinamide, which is a component of the coenzymes nicotinamide adenine dinucleotide (NAD) and its phosphate form, NADP. These coenzymes play an important role in tissue respiration and in glycogen, lipid, amino acid, protein, and purine metabolism. Although the exact mechanism of action by which niacin lowers cholesterol is not fully understood, it may act by inhibiting the synthesis of very low density lipoproteins (VLDL), inhibiting the release of free fatty acids from adipose tissue, increasing lipoprotein lipase activity, and reducing the hepatic synthesis of VLDL-C and LDL-C.
Tests
A modification of the Bethesda Assay where the pH and the protein concentration of the test mixture is further standardized, such that the factor VIII coagulant activity (FVIII:C) in the test mixture is less prone to artifactual deterioration and the test has improved specificity.
For professionals
Indicators
This gene plays a role in thyroid gene transcription.
Glossary Term
A reaction that contains all reagents except sample nucleic acid. Amplification in the NTC signals contamination of reagents or the environment, so NTC behavior is one of the first run-validity checks in any qPCR run log.
Pcr Terms
Glossary Term
Any part of a signal that is not the true or original signal but is introduced by the communication mechanism.
Performance Metrics
Glossary Term
A point mutation occurring within the protein-coding region of a gene, and which codes for a stop that can truncate the protein.
Pcr Terms
Glossary Term
A family of probability density functions whose mean, median and mode are identical. The function generates a symmetrical curve, whose position and shape is determined by its location and scale parameters, the mean and standard deviation respectively. The standard normal distribution has a location parameter of 0 and a scale parameter of 1.
Performance Metrics
Tests
A measurement of Norovirus genogroup I and/or II RNA present in a sample.
For professionals
Tests
A measurement of Norovirus genogroup I RNA present in a sample.
For professionals
Tests
A measurement of Norovirus genogroup II.4 IgG antibody present in a sample.
For professionals
Tests
A measurement of Norovirus genogroup II.4 IgM antibody present in a sample.
For professionals
Indicators
This gene is involved in intercellular signal transduction that plays a key role in development.
