Indicators
An antigen expressed by tissues derived from mullerian epithelium (tubal, endometrial and endocervical) or celomic epithelium (mesothelial cells of the pleura, pericardium and peritoneum). Although its biochemical nature has not been clearly defined, CA125 has been described as a glycosylated, high-molecular-weight protein that may be released from damaged cells. Measurable in plasma, CA125 is a sensitive, nonspecific tumor marker for ovarian cancer; as such it is much more useful for monitoring clinical responses to the treatment of ovarian cancer than for the diagnosis of ovarian cancer. Elevated plasma CA125 may occur in association with other malignancies and non-malignant gynecologic disorders. (NCI04)
Article
Research record from Anal Chem, 2026-06-04. PMID 42239998.
Article
Research record from J Pharm Biomed Anal, 2026-07-25. PMID 42520627.
Indicators
An animal sterol found in the body tissues (and blood plasma) of vertebrates. It can be found in large concentrations within the liver, spinal cord, and brain. Cholesterol is an important component of the membranes of cells, providing stability. It is the major precursor for the synthesis of vitamin D, of the various steroid hormones, including cortisol, cortisone, and aldosterone in the adrenal glands, and of the sex hormones progesterone, estrogen, and testosterone. Cholesterol also has an important role for the brain synapses as well as in the immune system. In conditions featuring elevated low density lipoproteins (LDL), cholesterol often forms plaque deposits in the walls of arteries, a condition known as atherosclerosis, which is a major contributor to coronary heart disease and other forms of cardiovascular disease.
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Cholinesterase (602 aa, ~68 kDa) is encoded by the human BCHE gene. This protein plays a role in choline metabolism.
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Research record from Cytometry B Clin Cytom, 2026-09-14. PMID 42740309.
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Research record from BMC Infect Dis, 2026-03-21. PMID 41864933.
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Research record from Front Immunol, 2026-07-08. PMID 42488664.
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Research record from Antimicrob Steward Healthc Epidemiol, 2026-07-06. PMID 42422873.
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Research record from Clin Chem Lab Med, 2026-07-10. PMID 42427067.
Indicators
Quantitative marker of cytomegalovirus replication used in transplant and immunocompromised care.
Indicators
Coagulation factor IX (461 aa, ~52 kDa) is encoded by the human F9 gene. This protein plays a role in the intrinsic pathway of blood coagulation through the mediation of proteolysis that converts factor X into an active protease.
