Glossary Term
Promoter
A DNA sequence at which RNA polymerase binds and initiates transcription.
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Glossary Term
A DNA sequence at which RNA polymerase binds and initiates transcription.
Tests
The determination of the ratio of pronormoblasts compared to total cells present in a sample. The measurement may be expressed as a ratio or percentage.
Tests
The determination of the amount of propionate in a sample.
Tests
The determination of the proprotein convertase subtilisin/kexin type 9 present in a sample.
Glossary Term
A type of study in which participants are enrolled into the study before they develop the disease or outcome in question.
Tests
The determination of the amount of the prostaglandin D2 synthase in a sample.
Tests
A measurement of the protein Wnt-10b activity in a sample.
Glossary Term
Refers to the total protein-encoding capability of an organism's genome. It is also used to refer to the actual total expressed protein complement of an organism or to the identifiable proteins of a single tissue or cell type or subcellular compartment.
Glossary Term
The global analysis of cellular proteins. Proteomics uses a combination of sophisticated techniques including two-dimensional (2D) gel electrophoresis, image analysis, mass spectrometry, amino acid sequencing, and bio-informatics to resolve comprehensively, to quantify, and to characterize proteins. The application of proteomics provides major opportunities to elucidate disease mechanisms and to identify new diagnostic markers and therapeutic targets.
Glossary Term
Nonfunctional DNA sequences that are very similar to the sequences of known genes. Many seem to have arisen as functional gene duplications that subsequently underwent mutation and loss of function. Others are structurally similar to mRNA and seem to have arisen by a reverse transcription event followed by integration into the genome. Some pseudogenes are transcribed and may play a role in regulation of its homologous gene.
Indicators
This gene is involved in tumor suppression and mutations in this gene have been associated with several cancers and cancer related diseases.
Indicators
This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription.