Glossary Term
Proteome
PCR TermsEN
Definition
Refers to the total protein-encoding capability of an organism's genome. It is also used to refer to the actual total expressed protein complement of an organism or to the identifiable proteins of a single tissue or cell type or subcellular compartment.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C18276. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Proteome
References
- NCI Thesaurus 26.09d — Proteome (C18276)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C18276. NCI definition, reproduced without modification under CC BY 4.0.
- Proteome-guided drug discovery maps and mitigates therapeutic degrader toxicity. — Nat Chem Biol, 2026-10-09 (PMID 42855516; literature)
- Proteome-wide chemotype profiling reveals the cysteinome as a pan-PTM hub. — Free Radic Biol Med, 2026-10-09 (PMID 42854993; literature)
- Mapping the functional dark proteome in cancer. — Nat Rev Cancer, 2026-10-08 (PMID 42850324; literature)
- Evolution and adaptations of the seminal proteome in an insect with traumatic insemination. — Mol Cell Proteomics, 2026-10-08 (PMID 42849879; literature)
- Functional diversification of the cephalopod proteome by RNA editing. — Cell, 2026-10-15 (PMID 42880282; literature)
- Global proteolysis during starvation governs proteome remodeling and a survival-regrowth trade-off in bacteria. — Proc Natl Acad Sci U S A, 2026-10-15 (PMID 42879477; literature)
- Effect of clarithromycin on the circulating inflammatory proteome in community-acquired pneumonia: a secondary analysis of the ACCESS trial. — Chest, 2026-10-17 (PMID 42892349; literature)
- Impact of clozapine on the proteome: A systematic review and functional analyses. — Schizophr Res, 2026-10-17 (PMID 42892068; literature)
- Joint 12th Asia Oceania Human Proteome Organization (AOHUPO), 8th Asia Oceania Agricultural Proteomics Organization (AOAPO), 3rd π-HuB Global Summit, 1st π-HuB Industry Conference and 13th China Human Proteome Organization (CNHUPO) Congress Report. — Proteomics, 2026-10-21 (PMID 42908276; literature)
- The proteome of Middle Pleistocene Xujiayao and common Denisovan morphology. — Nature, 2026-10-21 (PMID 42907507; literature)
- Plasma Angiotensin-Converting Enzyme as a Prioritized Candidate Target for Alzheimer's Disease: Evidence From Proteome-Wide Mendelian Randomization and a Large Prospective Cohort Study. — J Am Heart Assoc, 2026-10-23 (PMID 42924830; literature)
- The functional proteome landscape of a cosmopolitan oceanic bacterium. — Protein Cell, 2026-10-23 (PMID 42924431; literature)
- Preliminary proteome characterization of the aqueous humor across four cataract subtypes. — J Proteomics, 2026-10-25 (PMID 42927845; literature)
- Hippo Pathway Modulation Alters the Proteome and Migratory Phenotype of Prostate Cancer Cells. — Prostate, 2026-10-22 (PMID 42912183; literature)
- OpenAntigens: a structure-aware database for antigen construct design across the human cell-surface and secreted proteome. — Nucleic Acids Res, 2026-10-29 (PMID 42952403; literature)
- A nanoscale map of the human cell surface proteome reveals spatial and functional organization. — Nat Struct Mol Biol, 2026-10-28 (PMID 42951938; literature)