Glossary Term
Proteomics
Definition
The global analysis of cellular proteins. Proteomics uses a combination of sophisticated techniques including two-dimensional (2D) gel electrophoresis, image analysis, mass spectrometry, amino acid sequencing, and bio-informatics to resolve comprehensively, to quantify, and to characterize proteins. The application of proteomics provides major opportunities to elucidate disease mechanisms and to identify new diagnostic markers and therapeutic targets.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C20085. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-18. No individual clinical interpretation or human reviewer is asserted.
Also Known As
References
- NCI Thesaurus 26.09d — Proteomics (C20085)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C20085. NCI definition, reproduced without modification under CC BY 4.0.
- Targeted proteomics in late-onset neonatal sepsis: an exploratory analysis. — Pediatr Res, 2026-10-09 (PMID 42855463; literature)
- Proteomics analysis of small extracellular vesicles derived from human retinal Müller glial cells under high glucose condition. — Exp Eye Res, 2026-10-09 (PMID 42854891; literature)
- Corrigendum to "The combination of RNA-seq transcriptomics and data-independent acquisition proteomics reveal the mechanisms and function of different gooses testicular development at different stages of laying cycle" [Poultry Science, 103(10), 2024 Oct, 104007]. — Poult Sci, 2026-10-09 (PMID 42854498; literature)
- Corrigendum to "Novel insights into the mechanisms of seasonal cyclicity of testicles by proteomics and transcriptomics analyses in goose breeder lines" [Poultry Science, 103(11), 2024 Nov, 104213]. — Poult Sci, 2026-10-09 (PMID 42854497; literature)
- 4D-DIA proteomics unveils the dual engines of human sperm capacitation. — Reprod Biol, 2026-10-15 (PMID 42881083; literature)
- Apus enables automated end-to-end analysis and quality control of large-cohort proteomics data. — Cell Rep Methods, 2026-10-15 (PMID 42880256; literature)
- Meet the Editorial Team. An Interview With Garry Corthals, Editor-in-Chief, Proteomics and Proteomics Clinical Applications, University of Amsterdam, Amsterdam, Netherlands. — Proteomics, 2026-10-18 (PMID 42892754; literature)
- Tumour-proximal deep serum proteomics identifies biomarkers associated with ovarian cancer. — Mol Oncol, 2026-10-17 (PMID 42888903; literature)
- Joint 12th Asia Oceania Human Proteome Organization (AOHUPO), 8th Asia Oceania Agricultural Proteomics Organization (AOAPO), 3rd π-HuB Global Summit, 1st π-HuB Industry Conference and 13th China Human Proteome Organization (CNHUPO) Congress Report. — Proteomics, 2026-10-21 (PMID 42908276; literature)
- Quantifying Data Reuse in Proteomics Using PRIDE Downloads Statistics and a Semi-Supervised LLM-Based Framework. — Proteomics, 2026-10-21 (PMID 42908268; literature)
- Corrigendum to: Integrated quantitative proteomics and phosphoproteomics analysis reveals USP46-POU4F1-HPSE signaling axis in the pathogenesis of Hirschsprung disease. — Acta Biochim Biophys Sin (Shanghai), 2026-10-25 (PMID 42900565; literature)
- Metal-Organic Framework Assisted Sample Preparation Enables High-Depth Proteomics of Laser-Captured Trace Kidney Microregions. — Small Methods, 2026-10-23 (PMID 42924595; literature)
- Proteomics analysis reveals headgroup-dependent modulation of lipopolysaccharide-induced inflammation by arachidonoyl phospholipids in macrophages. — J Proteomics, 2026-10-24 (PMID 42925918; literature)
- Plasma Proteomics of Cancer Risk Among Patients with CKD. — Kidney360, 2026-10-23 (PMID 42912444; literature)
- Quantitative Top-Down Proteomics: A Review. — Mass Spectrom Rev, 2026-10-29 (PMID 42952329; literature)
- Transglutaminase dosage governs proteolytic kinetics and cleavage patterns during in vitro digestion of pea proteins: a proteomics-driven molecular analysis. — Int J Biol Macromol, 2026-10-28 (PMID 42950927; literature)
