Tests
Insulin-Like Growth Factor Binding Protein 2 Measurement
The determination of the amount of insulin-like growth factor binding protein 2 present in a sample.
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Tests
The determination of the amount of insulin-like growth factor binding protein 2 present in a sample.
Tests
The determination of the amount of insulin-like growth factor binding protein 3 present in a sample.
Indicators
Insulin-like growth factor I (195 aa, ~22 kDa) is encoded by the human IGF1 gene. This protein may be involved in the regulation of glucose metabolism.
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Interleukin-10 (178 aa, ~21 kDa) is encoded by the human IL10 gene. This protein plays a role in the negative regulation of cytokine expression.
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Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed of a 35-kD IL12A subunit (IL-6 Superfamily) and a 40-kDa IL12B subunit (Type I Cytokine Receptor 3 Family). IL12 stimulates T-cell-independent production of IFN-gamma by PBMCs, enhances NK cell lytic activity, acts as a growth factor for T- and NK-cells, and is important for Th1 and Th2 cell differentiation. Lymphocyte responses to IL12 require NOS2A and are mediated by STAT4 activator of transcription. (NCI)
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Interleukin-2 (153 aa, ~18 kDa) is encoded by the human IL2 gene. This protein is involved in T-cell proliferation, leukocyte stimulation and immune responses.
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Interleukin-4 (153 aa, ~17 kDa) is encoded by the human IL4 gene. This protein is involved in the regulation of the expression of class II MHC molecules, Fc receptors and cell surface-bound immunoglobulins.
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Interleukin-5 (134 aa, ~15 kDa) is encoded by the human IL5 gene. This protein plays a role in the growth and differentiation of both B-cells and eosinophils.
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Interleukin-6 (212 aa, ~24 kDa) is encoded by the human IL6 gene. This protein is involved in signaling affecting a wide variety of cell types including monocytes, lymphocytes, hepatocytes and nerve cells.
Tests
Iron tests measure different substances in the blood to check iron levels in your body. Iron is a mineral that your body needs for growth and development. Your body uses iron to make hemoglobin, a protein in red blood cells. It carries oxygen from the lungs to all parts of the body, Iron is also important for healthy muscles, bone marrow, and organ function. Your body also needs iron to make some hormones .
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Lactotransferrin (710 aa, ~78 kDa) is encoded by the human LTF gene. This protein is involved in the mediation of both proteolysis and iron transport.
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One of nine essential amino acids in humans (provided by food), Leucine is important for protein synthesis and many metabolic functions. Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. Leucine is available in many foods and deficiency is rare. (NCI04)