Indicator Explainer
Insulin-Like Growth Factor I
Insulin-like growth factor I (195 aa, ~22 kDa) is encoded by the human IGF1 gene. This protein may be involved in the regulation of glucose metabolism.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16743. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Insulin-Like Growth Factor I (C16743)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16743. NCI definition, reproduced without modification under CC BY 4.0.
- Histological Evaluation of Insulin-like Growth Factor-I in Experimental Intestinal Ischemia-Reperfusion Injury: A Rat Study. — Diseases, 2026-08-18 (PMID 42645108; literature)
- Correlation of Salivary Insulin-Like Growth Factor-I With the Middle Phalanx of the Third Finger (MP3) Skeletal Maturation Stages Across Pubertal Transitions: A Cross-Sectional Study. — Cureus, 2026-08-03 (PMID 42689151; literature)
- Distinguishing hyperparathyroidism from insulin-like growth factor I-driven calcium-phosphate metabolism changes in acromegaly. — Eur J Endocrinol, 2026-08-01 (PMID 42771820; literature)
- Size in small-for-gestational-age neonates correlates with insulin-like growth factor-binding protein proteolysis and insulin-like growth factor-I bioavailability. — J Endocr Soc, 2026-07-06 (PMID 42491477; literature)
- Editor's Note: Akt/mTOR Counteract the Antitumor Activities of Cixutumumab, an Anti-Insulin-like Growth Factor I Receptor Monoclonal Antibody. — Mol Cancer Ther, 2026-07-01 (PMID 42388043; literature)
- Muscle-derived insulin-like growth factor I cannot compensate for global Igf1 deficiency in mice. — Gen Comp Endocrinol, 2026-10-24 (PMID 42925913; literature)