Indicators
Complement C2
Complement C2 (752 aa, ~83 kDa) is encoded by the human C2 gene. This protein is involved in post-translational protein processing and complement activity.
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Indicators
Complement C2 (752 aa, ~83 kDa) is encoded by the human C2 gene. This protein is involved in post-translational protein processing and complement activity.
Indicators
Complement C3 (1663 aa, ~187 kDa) is encoded by the human C3 gene. This protein plays a role in complement-mediated immunity.
Tests
The determination of the amount of complement C3a DesArg present in a sample.
Tests
The determination of the amount of the complement C3c in a sample.
Tests
The determination of the amount of complement C4 present in a sample.
Tests
The determination of the amount of complement C4a present in a sample.
Indicators
Complement C5 (1676 aa, ~188 kDa) is encoded by the human C5 gene. This protein is involved in complement-mediated immunity.
Tests
The determination of the amount of complement C5a present in a sample.
Tests
The determination of the amount of complement C5b-9 present in a sample.
Indicators
A protein complex composed of 18 complement component 1q (C1q) subcomponent chains: six C1qA, six C1qB and six C1qC. The C1q complex is part of the complement component C1 complex (C1 complex) and undergoes confirmational rearrangement following binding of pentraxins or antigen-antibody complexes that include either immunoglobulin M (IgM) or several IgG molecules. These confirmational changes activate the C1r chains of the C1 complex, which, in turn, cleaves C1s chains of the C1 complex. Following C1s cleavage, the C1 complex can proteolytically activate C2 and C4 and promotes formation of C3-convertase, which cleaves C3 and activates the classical complement pathway.
Indicators
Complement component C6 (934 aa, ~105 kDa) is encoded by the human C6 gene. This protein is involved in complement-mediated host defense responses.
Indicators
Complement component C7 (843 aa, ~94 kDa) is encoded by the human C7 gene. This protein is involved in insertion of the membrane attack complex in lipid bilayers.