Indicators
BCL2 Gene
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Loading
Loading
Search products, companies, tests, and guides — go from query to quote request in one place.
Indicators
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicators
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Indicators
Beta-2-glycoprotein 1 (345 aa, ~38 kDa) is encoded by the human APOH gene. This protein is involved in binding to phospholipids, glycosaminoglycans and other negatively charged substances.
Indicators
Beta-2-microglobulin protein (119 aa, ~14 kDa) is encoded by the human B2M gene. This protein plays a role in immune responses and is a key component of major histocompatibility complex class I molecules. The protein is localized to the surface of cells and is utilized as a prognostic marker in persons with cancers that involve white blood cells. The polypeptide is also used as a marker in kidney damage diagnosis and in the detection of viral infection.
Indicators
Hexahydro-2-oxo-1H-thieno(3,4-d)imidazole-4-pentanoic acid. Growth factor present in minute amounts in every living cell. It occurs mainly bound to proteins or polypeptides and is abundant in liver, kidney, pancreas, yeast, and milk. The biotin content of cancerous tissue is higher than that of normal tissue.
Indicators
This gene is involved in cell cycle control, DNA repair and the maintenance of genomic stability. It also plays a role in the proliferation of embryonic cells.
Indicators
Proteins released into blood when heart muscle is injured; the central laboratory marker in suspected heart attack.
Indicators
An amino acid derivative. Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utilized as an energy substrate in all tissues except the brain.
Indicators
This gene plays a role in cell survival and the negative regulation of cell growth.
Indicators
A tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients and is used as a preservative. It is also used as an acidulant to control pH and acts as an anticoagulant by chelating calcium in blood.
Indicators
A non-essential amino acid. In hepatocytes, L-citrulline is synthesized in the urea cycle by the addition of carbon dioxide and ammonia to ornithine. L-citrulline is converted into L-arginine by the enzymes argininosuccinate synthetase and argininosuccinate lyase in the presence of L-aspartate and ATP. Subsequently, L-arginine is converted to nitric oxide by nitric oxide synthase and L-citrulline is regenerated as a by-product.
Indicators
Coagulation factor XII (615 aa, ~68 kDa) is encoded by the human F12 gene. This protein is involved in blood coagulation and fibrinolysis.