Indicators
The most abundant immunoglobulin G (IgG) subclass in the circulation of healthy individuals. The IgG1 core hinge sequence contains 15 amino acids and two interchain disulfide bonds. This subtype has high affinity for binding both Fc receptors and complement component C1q. IgG1 is the predominant antibody subclass that responds to antigens derived from both soluble and membrane proteins. Reduced levels of circulating IgG1 can indicate the presence of a variety of primary and secondary antibody deficiencies, which can result in hypogammaglobulinemia.
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This gene is involved in protein phosphorylation.
Tests
An immunoglobulins blood test measures the amount of immunoglobulins in your blood. Immunoglobulins are also called antibodies. Antibodies are proteins that your immune system makes to fight germs , such as viruses and bacteria . Your body makes different kinds of antibodies to fight germs in different parts of the body and at different stages of an infection.
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Article
Research record from iScience, 2026-04-28. PMID 42205694.
Tests
A measurement of the protein, lipid or small molecule aggregates located within the cytoplasm.
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Insulin (51 aa, ~6 kDa) is encoded by the human INS gene. This protein is involved in the direct regulation of glucose metabolism.
Tests
The determination of the amount of insulin-like growth factor binding protein 1 present in a sample.
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Tests
The determination of the amount of insulin-like growth factor binding protein 2 present in a sample.
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Tests
The determination of the amount of insulin-like growth factor binding protein 3 present in a sample.
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Indicators
Insulin-like growth factor I (195 aa, ~22 kDa) is encoded by the human IGF1 gene. This protein may be involved in the regulation of glucose metabolism.
Indicators
Interferon gamma (166 aa, ~19 kDa) is encoded by the human IFNG gene. This protein is involved in antiviral activity, macrophage activation, antiproliferative activity and immunopotentiation.
Tests
The determination of the amount of interferon regulatory factor 4 protein in a sample.
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