Indicators
STAT3 Gene
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
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Indicators
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
Indicators
This gene is involved in signal transduction and activation of transcription. It plays a role in the immune response via stimulation of T-cell proliferation.
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This gene plays a role in the regulation of both transcription and signaling.
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Tumor-associated oncofetal glycoprotein 72 (TAG-72) is a high molecular weight (220-400 kD) complex expressed by a wide variety of human adenocarcinomas. This antigen is expressed by a majority of invasive ductal breast carcinomas, and most colon, pancreatic, gastric, esophageal, lung (non-small cell), ovarian and endometrial adenocarcinomas, and on normal secretory endometrium, but not on other normal tissues. It is not expressed by leukemias, lymphomas, sarcomas, mesotheliomas, melanomas or benign tumors. The monoclonal antibodies against TAG-72 have been widely employed for the immunohistochemical analysis of adenocarcinomas as well as for radioimmunoscintigraphy and radioimmunoguided surgery.
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This gene is involved in cell cycle regulation and telomere maintenance.
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This gene is involved in transcriptional regulation and cell cycle progression regulation.
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This gene plays a role in cellular proliferation and mitogenic responses.
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Thyroglobulin (2768 aa, ~305 kDa) is encoded by the human TG gene. This protein is involved in thyroid hormone synthesis.
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Tissue-type plasminogen activator (562 aa, ~63 kDa) is encoded by the human PLAT gene. This protein plays a role in the cleavage of plasminogen between Arg-580 and Val-581 to form the fibrinolytic enzyme plasmin.
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This gene may play a role in the regulation of apoptosis.
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This gene plays a role in both transcriptional regulation and limb development.
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Transforming growth factor beta-1 (390 aa, ~44 kDa) is encoded by the human TGFB1 gene. This protein is involved in cell proliferation, cell death and a large number of signal transduction pathways.