Indicator Explainer
STAT3 Gene
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C24833. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — STAT3 Gene (C24833)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C24833. NCI definition, reproduced without modification under CC BY 4.0.
- [STAT3 gene-related hyper-IgE syndrome complicated by pulmonary aspergillosis: a case report]. — Zhonghua Jie He He Hu Xi Za Zhi, 2026-06-01 (PMID 42236459; literature)
- Peripheral Blood IL-6 and STAT3 Gene Expression as Biomarkers Associated with Neoadjuvant Chemotherapy Response in Triple-Negative Breast Cancer: A Prospective Cross-Sectional Study. — Breast Cancer (Dove Med Press), 2026-04-08 (PMID 41978660; literature)
- Genetic variations of STAT3 gene and their role in hodgkin lymphoma incidence. — Mol Biol Rep, 2026-02-20 (PMID 41718849; literature)
- A Novel Hypomorphic STAT3 Gene Variant in a 7-year-old Male with Hyper-IgE Syndrome. — J Clin Immunol, 2025-10-20 (PMID 41114900; literature)