Glossary Term
Promoter
A DNA sequence at which RNA polymerase binds and initiates transcription.
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Glossary Term
A DNA sequence at which RNA polymerase binds and initiates transcription.
Glossary Term
A type of study in which participants are enrolled into the study before they develop the disease or outcome in question.
Glossary Term
Refers to the total protein-encoding capability of an organism's genome. It is also used to refer to the actual total expressed protein complement of an organism or to the identifiable proteins of a single tissue or cell type or subcellular compartment.
Glossary Term
The global analysis of cellular proteins. Proteomics uses a combination of sophisticated techniques including two-dimensional (2D) gel electrophoresis, image analysis, mass spectrometry, amino acid sequencing, and bio-informatics to resolve comprehensively, to quantify, and to characterize proteins. The application of proteomics provides major opportunities to elucidate disease mechanisms and to identify new diagnostic markers and therapeutic targets.
Glossary Term
Nonfunctional DNA sequences that are very similar to the sequences of known genes. Many seem to have arisen as functional gene duplications that subsequently underwent mutation and loss of function. Others are structurally similar to mRNA and seem to have arisen by a reverse transcription event followed by integration into the genome. Some pseudogenes are transcribed and may play a role in regulation of its homologous gene.
Glossary Term
The minimum False Discovery Rate (FDR) value required for a test to be considered significant.
Glossary Term
Programs of regular assessment of medical and nursing activities to evaluate the quality of medical care including all actions taken to ensure that standards and procedures are adhered to and that delivered products or services meet performance requirements.
Glossary Term
Set of measurements and inspections taken to verify that performance of equipment and procedures remains within specified limits.
Glossary Term
Any of four equal-sized sets of observations in a ranked sample.
Glossary Term
The goodness of fit statistic for the terminal elimination phase.
Glossary Term
A study in which the participants are assigned by chance to separate groups to evaluate treatments. The study also includes a control group, which is undergoing the same rigors of the study with placebo treatment or standard treatment. The trial can also be controlled by the addition of a test group to ensure there are no factors present to skew the results and by the inclusion of peer-review analysis by appropriate government officials. 2005
Glossary Term
The difference between the lowest and highest numerical values; the limits or scale of variation.