Indicators
LZTR1 Gene
This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation.
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Indicators
This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation.
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This gene plays a role in signal transduction and regulation of transcription. It is also involved in cell differentiation, growth and proliferation.
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This gene plays a role in both protein phosphorylation and signal transduction.
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This gene plays a role in mediating cellular responses to growth factors, metabolic stimuli and mitogens.
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This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
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This gene plays a role in epidermal development and regulation of melanogenesis.
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This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.
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This gene plays a role in both cell cycle arrest and the inhibition of apoptosis.
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An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
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This gene is involved in transcriptional promotion in melanocytes.
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This gene plays a role in DNA mismatch repair.
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This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1.