Glossary Term
Sedimentation
The act or process of settling particles by mechanical means from a state of suspension in air or water.
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Glossary Term
The act or process of settling particles by mechanical means from a state of suspension in air or water.
Glossary Term
A collection of double stranded DNA fragments flanked by oligonucleotide sequence adapters to enable their analysis by high-throughput sequencing.
Glossary Term
Area of repetitive DNA within the genome consisting of multiple, end-to-end copies of a short DNA sequence usually comprised of di-, tri-, or tetranucleotide repeat units.
Glossary Term
A point mutation occurring within the protein-coding region of a gene, and which codes for the same amino acid as expected.
Glossary Term
A variation of a single nucleotide at a specific location of the genome due to base substitution, present at an appreciable frequency between individuals of a single interbreeding population.
Glossary Term
A variation of a single nucleotide at a specific location of the genome due to base substitution, which is found at any frequency in the population.
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A long linear single-stranded polymer formed from nucleotides attached to a deoxyribose backbone.
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A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
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The ability of a particular substance to dissolve in a particular solvent (yielding a saturated solution).
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A liquid that dissolves or that is capable of dissolving; the component of a solution that is present in greater amount.
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Any mutation with an origin in cells that are not destined to become gametes. As a consequence, such mutations are not transmitted to progeny, though they will be transmitted during any mitosis within the individual. Somatic mutations may contribute to a broad variety of pathologies including cancer.
Glossary Term
Any mutation that occurs within the discrete sequences comprising the 5' or 3' splice sites of a gene that has a spliced message. Splice-site mutation may result in a deletion or insertion of extraneous amino acids in the gene product or a change in the reading frame of the spliced message.