Glossary Term
Small Interfering RNA
PCR TermsEN
Definition
A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C2191. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
siRNASmall Interfering RNA
References
- NCI Thesaurus 26.09d — Small Interfering RNA (C2191)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C2191. NCI definition, reproduced without modification under CC BY 4.0.
- Small interfering RNA targeting protein Z-dependent protease inhibitor improves hemostasis in Von Willebrand factor- and Factor X-deficient mice. — Thromb Haemost, 2026-10-14 (PMID 42874635; literature)
- Small Interfering RNA in Cardiovascular Disease: A New Frontier in Precision Medicine. — Annu Rev Pharmacol Toxicol, 2026-10-07 (PMID 42842862; literature)
- Application of Dual-Targeting Carbon Dot Nanozymes in Improving Hypoxia and Enhancing Small Interfering RNA-Mediated Gene Silencing for Hepatocellular Carcinoma. — Biomater Res, 2026-10-19 (PMID 42898723; literature)