Glossary Term
Median
The value which has an equal number of values greater and less than it.
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Glossary Term
The value which has an equal number of values greater and less than it.
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Any physical object that is useful for prevention, diagnosis, monitoring, or treatment of disease or other conditions.
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A class of RNA molecule containing protein-coding information in its nucleotide sequence that can be translated into the amino acid sequence of a protein.
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The quantity and identity of all of the low molecular weight molecules in a biological entity or sample that are products of or participants in various metabolic processes.
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Metabolomics is the study of the biological metabolic profile of a cellular specimen in a specific environment at an isolated timepoint. This discipline depicts the physiological states of cells and organisms by focusing on carbohydrates, lipids, and other metabolites. Several analytical techniques are utilized to quantify the metabolic content of specimens such as mass spectrometry and electrophoretic applications.
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The covalent chemical or biochemical addition of a methyl group(s) to a compound. (NCI)
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A sequence of single-stranded RNA, that is 20-25 nucleotides in length, which is transcribed from DNA but is not translated into a protein. This nucleic acid may regulate the transcription or translation of other genes.
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Genomic instability associated with the presence of hypermutability in specific genetic marker regions resulting from defective DNA mismatch repair.
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A variety of simple di-, tri-, tetra-, and pentanucleotide tandem repeats that are dispersed in the euchromatic arms of most chromosomes.
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The mismatch repair (MMR) system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination. This function is critically dependent on the assembly of multimeric complexes involved in mismatch recognition and signal transduction to downstream repair events.
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A point mutation occurring within the protein-coding region of a gene, and which codes for a different amino acid than expected.
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Required or expected data that is not present, which may be due to non-completion or corruption.