Glossary Term
Methylation
PCR TermsEN
Definition
The covalent chemical or biochemical addition of a methyl group(s) to a compound. (NCI)
Extended Notes
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16848. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Also Known As
Methylation
References
- NCI Thesaurus 26.09d — Methylation (C16848)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16848. NCI definition, reproduced without modification under CC BY 4.0.
- Evaluation of mRNA expression and DNA methylation status of immune checkpoints in the peripheral blood of COVID-19 patients. — Epigenomics, 2026-10-18 (PMID 42893387; literature)
- IL-1β/IL-6 inflammatory crosstalk drives DNA methylation and histone remodeling associated with cytokine induced senescence in luminal breast cancer. — Inflamm Res, 2026-10-17 (PMID 42892641; literature)
- Intracranial extracerebral glioneuronal heterotopia with heterotopic cerebellum, glioependymal cyst, and DNA methylation profiling. — J Neuropathol Exp Neurol, 2026-10-21 (PMID 42906903; literature)
- Analytical Validation of MethyLiverDx-Sigma, a Plasma cfDNA Methylation Assay for Hepatocellular Carcinoma Detection. — Mol Cell Probes, 2026-10-21 (PMID 42906830; literature)
- Targeted long-read sequencing reveals allele-specific methylation profiles at the GNAS locus in pseudohypoparathyroidism with various etiologies. — J Bone Miner Res, 2026-10-24 (PMID 42925263; literature)
- How RNA methylation regulates jasmonic acid biosynthesis and plant aging. — Plant Cell, 2026-10-24 (PMID 42921836; literature)
- Differences in DNA Methylation Status Between Epithelial and Mesenchymal Phenotypes in Canine Malignant Mucosal Melanoma. — Vet Comp Oncol, 2026-10-25 (PMID 42928418; literature)
- DNMT3a Regulates the Proliferation and Apoptosis of Hepatocellular Carcinoma Cells Through RYBP Methylation. — Mol Carcinog, 2026-10-25 (PMID 42927609; literature)
- DNA methylation-based immune profiling reveals distinct subtypes in esophageal adenocarcinoma. — Eur J Cancer, 2026-10-28 (PMID 42950611; literature)
- Sleep-dependent DNA methylation remodeling in basolateral amygdala fear engrams. — Cell Rep, 2026-10-28 (PMID 42949914; literature)