Indicator Explainer
Plasminogen Activator Inhibitor 1
Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene. This protein plays a role in both cell adhesion and the modulation of plasmin activity.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C16947. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
Related Tests
Tests that measure or involve this indicator.
References
- NCI Thesaurus 26.09d — Plasminogen Activator Inhibitor 1 (C16947)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C16947. NCI definition, reproduced without modification under CC BY 4.0.
- Effects of probiotic and synbiotic supplementation on fibrinogen and plasminogen activator inhibitor-1 concentrations: A Grading of Recommendations Assessment, Development and Evaluation-based systematic review and meta-analysis. — J Int Med Res, 2026-10-07 (PMID 42844594; literature)
- The relationship between plasminogen activator inhibitor-1 levels and blood pressure in adolescents with a history of prematurity and/or low birth weight. — Pediatr Nephrol, 2026-09-09 (PMID 42714585; literature)
- Plasminogen Activator Inhibitor-1 Deficiency Exacerbates Pressure Overload-Induced Cardiac Hypertrophy in Mice. — J Am Heart Assoc, 2026-10-23 (PMID 42924834; literature)
- Chemokine receptor CXCR2 and plasminogen activator inhibitor-1 expression in colorectal adenocarcinoma are associated with prognostic features. — Clin Transl Oncol, 2026-10-23 (PMID 42909795; literature)