Indicator Explainer
Osmolality
The concentration of osmoles of solute per kilogram of solvent present in a sample.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C89824. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Osmolality (C89824)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C89824. NCI definition, reproduced without modification under CC BY 4.0.
- High urine osmolality and elevated urine sodium predict early nonresponse to fluid restriction in patients with the syndrome of inappropriate antidiuresis. — J Intern Med, 2026-10-07 (PMID 42841275; literature)
- Mediation Analysis of Urine Osmolality and Response to Tolvaptan in Autosomal Dominant Polycystic Kidney Disease: A Post Hoc Assessment. — Nephrology (Carlton), 2026-10-01 (PMID 42813962; literature)
- Association Between Admission Calculated Serum Osmolality and New-Onset Atrial Fibrillation in Patients with Non-ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention. — Diagnostics (Basel), 2026-10-16 (PMID 42938205; literature)
- Oxidative stress increases aquaporin-2 membrane accumulation in renal epithelial cells and urine osmolality in tolvaptan-induced nephrogenic diabetes insipidus. — Am J Physiol Renal Physiol, 2026-10-16 (PMID 42932912; literature)