Indicator Explainer
Haptoglobin
Haptoglobin (406 aa, ~45 kDa) is encoded by the human HP gene. This protein plays a role in tight junction disassembly, intestinal permeability, heme iron recycling, antimicrobial activity and the regulation of hydrogen peroxide catabolism.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C37962. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-19. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Haptoglobin (C37962)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C37962. NCI definition, reproduced without modification under CC BY 4.0.
- Dried-blood haptoglobin as a prognostic biomarker for bovine respiratory disease in feedlot beef calves. — Can Vet J, 2026-10-01 (PMID 42846833; literature)
- Haptoglobin and serum amyloid a as diagnostic biomarkers for differentiating pregnancy from pseudopregnancy in dromedary camels. — Theriogenology, 2026-09-25 (PMID 42804869; literature)
- Association of Haptoglobin Genotype with Cardiovascular Disease and Left Ventricular Ejection Fraction in Kidney Transplant Recipients. — J Clin Med, 2026-09-28 (PMID 42881997; literature)
- Therapeutic potential of haptoglobin in a murine model of sickle cell anemia. — PLoS One, 2026-09-18 (PMID 42758770; literature)