Indicator Explainer
Growth/Differentiation Factor 15
Growth/differentiation factor 15 (308 aa, ~34 kDa) is encoded by the human GDF15 gene. This protein plays a role in both tissue differentiation and signal transduction.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C34026. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
Related Tests
Tests that measure or involve this indicator.
References
- NCI Thesaurus 26.09d — Growth/Differentiation Factor 15 (C34026)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C34026. NCI definition, reproduced without modification under CC BY 4.0.
- Growth differentiation factor 15 ameliorates alcohol-associated liver disease by diminishing the glycolytic metabolism of neutrophils. — Gut, 2026-10-20 (PMID 42901759; literature)
- Temporal regulation of activin, follistatin, and growth differentiation factor 15 in the liver and circulation during high-fat diet-induced fatty liver disease. — Korean J Physiol Pharmacol, 2026-10-07 (PMID 42838888; literature)
- Effect of conditions and diseases associated with systemic inflammation on the plasma concentration of growth differentiation factor 15 (GDF15) in dairy cows. — J Dairy Sci, 2026-10-22 (PMID 42913831; literature)
- Metformin and caffeic acid phenethyl ester counteract hyperglycemia-induced endothelial dysfunction through growth differentiation factor 15 and heme oxygenase-1-associated signaling. — Biochem Biophys Rep, 2026-10-06 (PMID 42893040; literature)
- Serum Growth Differentiation Factor 15 Levels in School-Aged Children Born Preterm. — Acta Paediatr, 2026-10-06 (PMID 42837197; literature)