Indicator Explainer
Cystatin-B
Cystatin-B (98 aa, ~11 kDa) is encoded by the human CSTB gene. This protein is involved in the regulation of cathepsins.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C128872. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Cystatin-B (C128872)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C128872. NCI definition, reproduced without modification under CC BY 4.0.
- Beyond traditional biomarkers: do serum cystatin C and urinary cystatin B improve diagnostic precision in feline and canine renal disease? A systematic review and meta-analysis. — Front Vet Sci, 2026-07-03 (PMID 42491500; literature)
- Genome-wide identification of the cystatin gene family and functional characterization of cystatin B in flathead mullet (Mugil cephalus). — Fish Shellfish Immunol, 2026-06-25 (PMID 42349697; literature)
- Oxidative Stress Drives Cell Cycle Stalling, Apoptosis and Metabolic Suppression in Cystatin B Deficient EPM1 Patient iPSCs. — Cell Prolif, 2026-05-19 (PMID 42153509; literature)
- Mendelian Randomization to Examine the Causal Effects of Cystatin on Ovarian Lesions. — Int J Womens Health, 2026-05-15 (PMID 42164282; literature)
- Cystatin B Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting the JAK2/STAT3 Signaling Pathway. — CNS Neurosci Ther, 2026-04-01 (PMID 41906531; literature)
- Serum fetuin A and cystatin B as biomarkers among autism spectrum disorder patients in central India. — Bioinformation, 2026-02-28 (PMID 42109364; literature)