Indicator Explainer
Anti-La Antibody
An antinuclear antibody directed against a 47 kDa RNA-binding protein in the nucleus. They can be associated with Sjogren syndrome and system lupus erythematosus. Maternal anti-La antibody positivity can be associated with neonatal lupus.
This page explains what the indicator is and how results are interpreted in general terms. Reference ranges depend on the laboratory, the method, and your own situation — no single “normal value” applies to everyone. This page is health information, not a diagnosis. For symptoms, treatment, or urgent concerns, contact a healthcare professional.
When it is tested
Source: National Cancer Institute, NCI Thesaurus 26.09d, C121323. NCI definition, reproduced without modification under CC BY 4.0. Source identity and definition checked automatically on 2026-10-20. No individual clinical interpretation or human reviewer is asserted.
Reading results
Reference intervals and interpretation depend on the laboratory, specimen, method and clinical context. This source definition is educational information; it does not establish a diagnosis, product approval or suitability for an individual.
Also Known As
References
- NCI Thesaurus 26.09d — Anti-La Antibody (C121323)
- Source: National Cancer Institute, NCI Thesaurus 26.09d, C121323. NCI definition, reproduced without modification under CC BY 4.0.
- Association between maternal anti-Ro and anti-La antibody levels and congenital heart block: a 20-year cohort study. — Arch Gynecol Obstet, 2026-02-21 (PMID 41721052; literature)
- Clinical Implications of Antinuclear Antibody (ANA) and Anti-Ro/Anti-La Antibody Profile in Patients with Primary Sjögren's Syndrome: A Multicenter Cross-Sectional Study of a National Egyptian Cohort. — Open Access Rheumatol, 2025-07-14 (PMID 40688384; literature)