Indicadores
STAT3 Gene
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
Loading
Loading
Busque productos, empresas, pruebas y guías: pase de la consulta a la solicitud de cotización en un solo lugar.
Indicadores
This gene plays a role in signal transduction and activation of transcription. It is involved in regulation of both apoptosis and cell growth.
Indicadores
Exhibiting a broad range of biological activities on T and natural killer cells, Interleukin-12 is a disulfide-bonded heterodimeric cytokine composed of a 35-kD IL12A subunit (IL-6 Superfamily) and a 40-kDa IL12B subunit (Type I Cytokine Receptor 3 Family). IL12 stimulates T-cell-independent production of IFN-gamma by PBMCs, enhances NK cell lytic activity, acts as a growth factor for T- and NK-cells, and is important for Th1 and Th2 cell differentiation. Lymphocyte responses to IL12 require NOS2A and are mediated by STAT4 activator of transcription. (NCI)
Indicadores
A heterodimeric cytokine composed of interleukin-12 subunit beta and interleukin-23 subunit alpha. This complex binds to the interleukin-23 receptor complex, which activates the JAK-STAT signaling pathway and modulates the proliferation, differentiation and effector functions of T-lymphocytes, natural killer cells and some myeloid lineage cells.
Indicadores
A product of hemoglobin produced by oxidation of the iron atom from the ferrous to the ferric state.