Indicadores
APC Gene
This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.
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Indicadores
This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.
Indicadores
This gene may be involved in both transcriptional regulation and chromatin remodeling.
Indicadores
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicadores
This gene functions as a tumor suppressor and transcriptional regulator.
Indicadores
This gene plays a regulatory role in transcription, cellular maintenance and hematopoiesis.
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This gene plays a regulatory role in transcription and in matrix metalloproteinase activity.
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A derivative of the natural macrocyclic lactone sirolimus with immunosuppressant and anti-angiogenic properties. In cells, everolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target of Rapamycin (mTOR), a key regulatory kinase. Inhibition of mTOR activation results in the inhibition of T lymphocyte activation and proliferation associated with antigen and cytokine (IL-2, IL-4, and IL-15) stimulation and the inhibition of antibody production. (NCI05)
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This gene may be involved in Golgi stabilization, embryogenesis or transcriptional regulation.
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This gene plays a role in both cell cycle arrest and the inhibition of apoptosis.
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This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions.
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This gene plays a regulatory role in megakaryocytopoiesis and platelet formation.
Indicadores
This gene plays a regulatory role in muscle contraction and the required ATP hydrolysis.