Indicadores
AKT1 Gene
This gene is involved in signal transduction and negative regulation of apoptosis. It also plays a role in glucose transport, glycogen synthesis, protein synthesis and neuronal survival.
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Indicadores
This gene is involved in signal transduction and negative regulation of apoptosis. It also plays a role in glucose transport, glycogen synthesis, protein synthesis and neuronal survival.
Indicadores
This gene plays a role in glucose homeostasis and the inhibition of apoptosis.
Indicadores
This gene is involved in signal transduction and the inhibition of apoptosis.
Indicadores
This gene is involved in apoptosis, DNA repair and cell cycle regulation.
Indicadores
This gene is involved in apoptotic regulation. Overexpression of this gene promotes the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.
Indicadores
This anti-apoptotic gene regulates apoptotic activity. BIRC3 gene promotes tumor cell survival.
Indicadores
This gene is involved in cell organization/biogenesis and the inhibition of apoptosis.
Indicadores
This gene plays a role in apoptotic regulation.
Indicadores
This gene plays a role in signal transduction, regulation of transcription and enhancement of apoptosis.
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A cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c and caspases 8 and 3. (NCI04)
Indicadores
This gene is involved in signal transduction and apoptosis.
Indicadores
This gene plays a role in several cellular processes related to cellular viability; including the cell cycle and apoptosis.