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Artículo
Research record from Genes (Basel), 2026-07-31. PMID 42650100.
Glossary Term
A genetic variation where gain, loss, or exchange of DNA results in monoallelic loss of function mutations in a diploid cell. In the context of tumor suppressor genes, where a single copy is sufficient for functionality, loss of function for the second allele is associated with tumorigenesis.
Indicadores
This gene is involved in transcriptional regulation and has tumor suppressor activity.
Artículo
Research record from Mol Diagn Ther, 2026-07-06. PMID 42410176.
Indicadores
This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are associated with a variety of hematopoietic tumors, leukemias and lymphomas.
Indicadores
This gene is involved in transcriptional regulation and amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.
Artículo
Research record from NPJ Precis Oncol, 2026-04-21. PMID 42014803.
Artículo
Research record from Clin Cancer Res, 2026-10-01. PMID 42223536.
Artículo
Research record from BMC Cancer, 2026-07-17. PMID 42464142.
Artículo
Research record from Cancer Med, 2026-10-01. PMID 42839555.
Pruebas
A PD-L1 test uses a sample of cancerous tumor tissue to measure how much of a protein called programmed-death ligand 1 (PD-L1) is found on the cancer cells. Normally, PD-L1 is found on certain healthy cells. It helps keep your immune system from attacking healthy tissue by acting as a kind of "brake" on your immune system cells (called T-cells). However, in some cancers, PD-L1 keeps your immune system from attacking cancerous cells.
Artículo
Research record from Pract Lab Med, 2026-05-07. PMID 42200146.
