Artículo
Validation of a microsampling-compatible liquid-liquid extraction method for cannabinoid quantitation in 50 µL of whole blood using liquid chromatography-mass spectrometry.
Research record from J Anal Toxicol, 2026-04-01. PMID 41520150.
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Artículo
Research record from J Anal Toxicol, 2026-04-01. PMID 41520150.
Artículo
Research record from J Mol Diagn, 2026-07-20. PMID 42476499.
Artículo
Research record from Oncol Rep, 2026-09-18. PMID 42757462.
Artículo
Research record from Ann Lab Med, 2026-08-28. PMID 42661591.
Technology
Check PCR instrument compatibility by fluorescence channels, reaction format support, software fit and validation effort.
Artículo
Build zoonotic disease surveillance that survives quiet years: sentinel site design, portable assay menus, validation discipline, and honest procurement planning.
Glossary Term
Validation evidence that an assay detects the range of variants, genotypes, or serotypes it claims to cover. For evolving targets such as influenza or SARS-CoV-2, inclusivity statements carry a validation date and should be checked against circulating variant lists at procurement time.
Glossary Term
How close amplification is to ideal doubling each cycle, reported as a percentage or derived from the standard curve slope. Efficiency near 90–110% with a linear standard curve supports quantification claims; it is a standard checklist item when auditing assay validation dossiers.
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Request catalogs, buyer toolkits, tender documents, validation checklists, and partner packs for IVD sourcing.
Technology
Check assay-to-instrument fit by fluorescence channels, reaction format and software compatibility across installed PCR platforms.
Technology
Variation occurring within a species in the length of DNA fragments generated by a specific endonuclease. Such variations are generated by mutations that create or abolish recognition sites for these enzymes.
Technology
A procedure used to demonstrate nucleotide sequence variations that occur in the same region of DNA between individuals within a species, or between alleles in an individual to detect mutations in various genes, such as oncogenes, tumor suppressor genes, or genes responsible for genetic diseases. The method detects different conformations adopted by partially denatured DNA fragments resulting from their specific nucleotide sequences under denaturing conditions. Denatured single-stranded DNA fragments are allowed to partially renature without formation of double-stranded DNA. The particular conformations adopted by each of the renatured fragments depend on each of their specific nucleotide sequences. The fragments are run on polyacrylamide gels to detect subtle changes in migration due to their particular secondary structures. Resulting fragment band in the gel will misalign if any point mutations are present to alter the conformation.