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Pruebas
A proprietary enzyme-linked immunosorbent assay for semi-quantitative detection of IgG antibodies against SARS-CoV-2 using a modified nucleocapsid protein (NCP) containing only diagnostically relevant epitopes.
Pruebas
A proprietary enzyme-linked immunosorbent assay for quantitative detection of IgG antibodies against SARS-CoV-2 using the S1 domain of the spike protein, including the receptor binding domain (RBD).
Pruebas
A measurement of the German cockroach (Blattella germanica) antigen IgG antibody in a biological specimen.
Pruebas
The determination of the amount of hepatitis B virus core IgG antibody in a biological specimen.
Pruebas
The determination of the amount of Herpes Simplex virus 1 IgG antibody present in a sample.
Indicadores
An immunoglobulin isotype (subclass) that characterizes secondary immune responses. This isotype is further broken down into several smaller subclasses (IgG1, IgG2a, IgG2b, IgG3 in the mouse; IgG1-4 in the human), and each subclass is differentially synthesized and secreted into the serum upon differential immune stimuli.
Indicadores
The most abundant immunoglobulin G (IgG) subclass in the circulation of healthy individuals. The IgG1 core hinge sequence contains 15 amino acids and two interchain disulfide bonds. This subtype has high affinity for binding both Fc receptors and complement component C1q. IgG1 is the predominant antibody subclass that responds to antigens derived from both soluble and membrane proteins. Reduced levels of circulating IgG1 can indicate the presence of a variety of primary and secondary antibody deficiencies, which can result in hypogammaglobulinemia.
Indicadores
The second most abundant immunoglobulin G (IgG) subclass in the circulation of healthy individuals. The IgG2 core hinge sequence contains 12 amino acids and up to four interchain disulfide bonds. This subtype has low affinity for binding both Fc receptors and complement component C1q. The production of this IgG2 is stimulated by exposure to bacterial capsular polysaccharides and other antigenic glycans.
Pruebas
The determination of the total amount of IgG and IgM present in a sample.
Pruebas
The determination of a sub-population of IgG positive plasmablasts in a sample.
Pruebas
The determination of the ratio of a sub-population of IgG positive plasmablasts to total IgG positive plasmablasts present in a sample. The measurement may be expressed as a ratio or percentage.
Pruebas
The determination of the ratio of IgG compared to albumin present in a sample. The measurement may be expressed as a ratio or percentage.
