Glossary Term
Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription. NER is targeted to actively transcribed regions of the genome. During NER in eukaryotes, shape irregularities are detected by protein complexes that slide along the DNA molecule and induce cuts on each side of a lesion several nucleotides away. Removal of the damaged 25-30 nucleotide fragment is followed by repair synthesis and ligation.
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Artículo
Research record from Diagnostics (Basel), 2026-10-07. PMID 42882387.
Glossary Term
A DNA polymer made up of a small number of nucleotides.
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Glossary Term
Short DNA oligonucleotide chains used to prime DNA (and in some cases RNA) synthesis.
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Artículo
Research record from Int J Mol Sci, 2026-03-07. PMID 41828687.
Glossary Term
A sequence of nucleotides in that contains no termination codons and so can potentially translate as a polypeptide chain.
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Research record from Emerg Infect Dis, 2026-03-01. PMID 41863542.
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Research record from Parasit Vectors, 2026-06-29. PMID 42374591.
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Research record from Mol Biol Rep, 2026-07-15. PMID 42455225.
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Research record from Med Mycol, 2026-08-01. PMID 42593422.
Artículo
Research record from Clin Infect Dis, 2026-06-11. PMID 42272071.
Glossary Term
The concentration of osmoles of solute per kilogram of solvent present in a sample.
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