Glossary Term
Small Interfering RNA
A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
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Glossary Term
A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
Indicadores
This gene is involved in guanine nucleotide exchange.
Pruebas
A determination of the number of transcript splice junctions based on nucleotide sequencing reads extending across the start and/or end of a junction.
Glossary Term
A stretch of repetitive nucleotide sequences (TTAGGG repeats in humans) found at both ends of each chromatid arm that plays a role in chromosome stability during replication.
Glossary Term
A class of short adaptor RNAs that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation. Each transfer RNA comprises a three-nucleotide sequence that is complementary to the triplet nucleotide coding sequence of an mRNA, conferring specificity to the amino acid being incorporated into the assembling protein.
Glossary Term
Short random nucleotide sequences that are ligated to each primer molecule during amplification of a nucleotide sample during library preparation to act as a unique tag. Their use helps to identify PCR duplicates in sequencing data.
Indicadores
A family of phosphatases that add monophosphates to substrates. The optimal pH for activity of these enzymes is below 7.
Pruebas
The determination of cellular CD73 expression in a biological specimen.