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Artículo
Research record from J Med Virol, 2026-04-01. PMID 41944344.
Indicadores
A non-essential amino acid in humans (synthesized by the body), Serine is present and functionally important in many proteins. With an alcohol group, serine is needed for the metabolism of fats, fatty acids, and cell membranes; muscle growth; and a healthy immune system. It also plays a major role in pyrimidine, purine, creatine, and porphyrin biosynthetic pathways. Serine is also found at the active site of the serine protease enzyme class that includes trypsin and chymotrypsin. (NCI04)
Pruebas
The determination of the amount of neuron specific enolase present in a serum sample.
Pruebas
An immunoassay that is used to determine the amount of soluble interleukin-2 receptor subunit alpha in a patient serum sample. High levels of the soluble form of the receptor can be indicative of hematological malignancies and other neoplastic disorders.
Indicadores
This gene is involved in epigenetic control of gene expression through histone methylation.
Pruebas
The determination of the amount of severe acute respiratory syndrome coronavirus 2 antibody in a sample.
Pruebas
The determination of the amount of severe acute respiratory syndrome coronavirus 2 in a sample.
Artículo
Research record from J Pharm Biomed Anal, 2026-06-25. PMID 42378913.
Indicadores
A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
Pruebas
The determination of the amount of soluble interleukin 2 receptor activity present in a sample.
Indicadores
This gene is involved in embryonic development and in the determination of cell fate.
Indicadores
A secreted antigen derived from two nearly identical cytoplasmic glycoproteins of the serpin family, serpin B3 (SCCA-1) and serpin B4 (SCCA-2). These proteins are specifically expressed in normal squamous epithelia and are present at elevated concentrations in the serum of subjects with squamous cell carcinoma and certain inflammatory and autoimmune diseases. This antigen was first described in squamous cell cervical carcinoma; it is currently used as a nonspecific tumor marker for the presence, staging and monitoring of the disease course for squamous cell carcinomas of the head and neck, cervix, esophagus, anus and lung.
