Indicadores
A long-acting barbituric acid derivative with antipsychotic property. Phenobarbital binds to and activates the gamma-aminobutyric acid (GABA)-A receptor, thereby mimicking the inhibitory actions of GABA in the brain. The activation effects of the phenobarbital-receptor-ionophore complex include increased frequency of chloride channel openings, membrane hyperpolarization and ultimately synaptic inhibition and decreased neuronal excitability. In addition, this agent inhibits glutamate induced depolarization.
Indicadores
A hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.
Pruebas
The determination of the amount of plasmin alpha-2 antiplasmin complex in a sample.
For professionals
Indicadores
Platelet-activating factor acetylhydrolase (441 aa, ~50 kDa) is encoded by the human PLA2G7 gene. This protein is involved in platelet-activating factor metabolism.
Pruebas
The determination of the amount of PMS1 homolog 2 present in a sample.
For professionals
Indicadores
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
Indicadores
Prostaglandin-H2 D-isomerase (190 aa, ~21 kDa) is encoded by the human PTGDS gene. This protein is involved in the conversion of prostaglandin H2 (PGH2) to prostaglandin D2 (PGD2).
Artículo
Research record from Medwave, 2026-05-15. PMID 42139648.
Pruebas
Multiplex PCR detecting 10–20+ respiratory viruses and atypical bacteria from one specimen.
For everyone & professionals
Indicadores
The fat soluble vitamin retinol. Vitamin A binds to and activates retinoid receptors (RARs), thereby inducing cell differentiation and apoptosis of some cancer cell types and inhibiting carcinogenesis. Vitamin A plays an essential role in many physiologic processes, including proper functioning of the retina, growth and differentiation of target tissues, proper functioning of the reproductive organs, and modulation of immune function.
Pruebas
The determination of the amount of retinol binding protein 2 in a sample.
For professionals
Glossary Term
A two-step setup in which RNA is first copied into complementary DNA by a reverse transcriptase and then amplified by PCR. Used for RNA viruses such as influenza, RSV, SARS-CoV-2, and HCV. In procurement documents, confirm whether "RT-PCR" refers to real-time (quantitative) or endpoint (qualitative) reading.
Pcr Terms
