Indicadores
JAK3 Gene
This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
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Indicadores
This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
Indicadores
The levorotatory isomer of the aromatic amino acid tyrosine. L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine. It is considered a non-essential amino acid; however, in patients with phenylketonuria who lack phenylalanine hydroxylase and cannot convert phenylalanine into tyrosine, it is considered an essential nutrient. In vivo, tyrosine plays a role in protein synthesis and serves as a precursor for the synthesis of catecholamines, thyroxine, and melanin.
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This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions.
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This gene is involved in cellular differentiation and neurotrophic functions.
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This gene plays a regulatory role in synaptic functions and in the long-term potentiation of brain synapses.
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This gene plays a role in neuronal development and cellular differentiation. Mutations in the gene are associated with medulloblastomas, secretory breast carcinomas and other cancers.
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This gene plays a role in mitogenic activities affecting mesenchymal cells and is involved in receptor tyrosine kinase signal transduction.
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An essential aromatic amino acid in humans (provided by food), Phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. The L-form of Phenylalanine is incorporated into proteins, while the D-form acts as a painkiller. Absorption of ultraviolet radiation by Phenylalanine is used to quantify protein amounts. (NCI04)
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This gene plays a role in the regulation of cell signaling. It is involved in cell migration, metabolic control, mitogenic activation and gene transcription.
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This gene plays a role in receptor tyrosine phosphorylation signal transduction, and is thought to play a role in cellular growth or differentiation, but an exact function has not been substantiated.
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This gene is involved in apoptosis, hormonogenesis, focal adhesion and the formation of intercellular junctions.
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A hormone synthesized and secreted by the thyroid gland containing four iodine atoms and is converted to triiodothyronine (T3) in the body, influencing metabolism and organ function.