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Indicadores
A fusion gene that results from a translocation t(9;22)(q34;q11) that fuses the 5' part of the BCR gene to the 5' side of exon 2 of the ABL1 gene. There are 3 potential products that are formed depending on which BCR exon has the breakpoint. All of the protein products have constitutively active tyrosine kinase activity. This fusion is associated with both chronic myeloid leukemia and acute lymphoblastic leukemia.
Indicadores
This gene is involved in both signaling and B-cell development.
Indicadores
This gene plays a role in cellular proliferation and is involved in the oncogenic process through amplification and/or overexpression in several cancers.
Indicadores
This gene is involved in signal transduction pathways that result in cellular proliferation or differentiation. The gene has also been associated with numerous cancers.
Indicadores
This gene is involved in neuronal development and plays a role in receptor tyrosine kinase signal transduction that regulates cellular proliferation and differentiation.
Indicadores
This gene plays a role in mitogenesis and differentiation.
Indicadores
This gene plays a role in hematopoiesis and may function as a growth factor receptor.
Pruebas
A measurement of the FMS-like tyrosine kinase 3 ligand in a sample.
Indicadores
This gene plays a role in non-receptor tyrosine protein kinase-mediated signal transduction.
Indicadores
This gene is involved in erythropoiesis and signal transduction.
Indicadores
This gene plays a role in signal transduction and non-receptor tyrosine protein kinase activity.
Indicadores
This gene plays a regulatory role in the modulation of cell-surface receptors and hepatocyte growth factor interactions.
