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An ANA test is a blood test that looks for antinuclear antibodies in your blood. Antibodies are proteins that your immune system makes to fight foreign substances, like viruses and bacteria. But an antinuclear antibody attacks your healthy cells instead. It's called "antinuclear" because it targets the nucleus of the cells, which is in charge of sending signals that are needed for important cell functions.
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This gene plays a role in signal transduction. It is involved in both adhesion and migration of cells.
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This gene is involved in signal transduction and plays a role in development.
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This gene plays a role in the bone morphogenetic protein signaling pathway.
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This gene is involved in both signaling and B-cell development.
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C peptide (31 aa, ~3 kDa) is encoded by the human INS gene. This protein is involved in both signal transduction and the modulation of blood flow.
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This gene is involved in G-protein-coupled receptor signaling and calcium homeostasis.
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A protein complex comprised of one T-cell surface glycoprotein CD3 delta chain (CD3D), one T-cell surface glycoprotein CD3 gamma chain (CD3G) and two T-cell surface glycoprotein CD3 epsilon chains (CD3E). CD3D, CD3G and CD3E are transmembrane proteins with one extracellular immunoglobulin domain and one intracellular ITAM domain. The CD3 complex is a T-cell co-receptor that noncovalently associates with either the disulfide bound heterodimeric alpha/beta T-cell receptor (TCR) or gamma/delta TCR and two copies of the accessory protein, T-cell surface glycoprotein CD3 zeta chain (CD247), which is a transmembrane protein with three ITAM domains. The TCR moiety of the TCR-CD3 complex binds to MHC and processed antigens on antigen presenting cells, which triggers phosphorylation of and cellular propagation of the signal by CD247 and the CD3 complex.
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This gene is involved in both cell adhesion and cell-cell signaling.
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This gene is involved in both signal transduction and the metabolism of ADP-ribose.
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This gene plays a role in transcriptional regulation and in NF-kappa B signal transduction.
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This gene is involved in signal transduction and regulation of transcription.
