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Research record from Cancer Rep (Hoboken), 2026-07-01. PMID 42463449.
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Prenatal cell-free DNA (cfDNA) screening is a blood test given during pregnancy . During pregnancy, some of the fetus's DNA circulates in the mother's bloodstream. A cfDNA screening checks this DNA to find out if the baby is more likely to have certain conditions caused by an abnormal number of chromosomes , such as Down syndrome .
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A prenatal panel is a group of blood tests done in early pregnancy . The tests check for diseases and infections that can affect the health of you and your developing baby . The results of the tests can guide treatments, which may help prevent serious complications. A prenatal panel usually includes the following tests:
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A progesterone test measures the level of progesterone in a sample of your blood. Progesterone is a hormone that's made mainly by the ovaries, which are two glands in the female reproductive system that contain eggs.
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An RBC (red blood cell) antibody screen is a blood test that looks for RBC antibodies in your blood. These antibodies destroy red blood cells that are foreign (different from your own).
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Syphilis tests generally look for certain antibodies in your blood. Antibodies are proteins that your immune system makes when it finds harmful substances in your body. In this case, the harmful substance is the bacterium that causes syphilis , one of the most common sexually transmitted infections (STIs.)
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A Zika virus test looks for signs of the Zika infection in your blood or urine. Zika is a type of flavivirus, as is dengue fever and West Nile . Like those viral infections , Zika is usually spread by mosquitoes , especially in areas with tropical climates, such as parts of Central and South America, Africa, Mexico, and islands in the Caribbean and Pacific. Because Zika can enter bodily fluids such as blood, urine (pee), and semen, it can also spread through sex with an infected person or from a pregnant woman to her fetus.
