Indicadores
PMS2 Gene
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
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Indicadores
This gene is involved in mismatch repair and mutations in the gene result in hereditary non-polyposis colon cancer 4.
Indicadores
This gene is involved in tumor suppression and mutations in this gene have been associated with several cancers and cancer related diseases.
Indicadores
This gene plays an essential role in neural crest development, cellular growth and differentiation. Mutations in the gene are associated with a variety of neoplasias and carcinomas.
Indicadores
A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.