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This gene plays a role in cell cycle progression and apoptosis. Cytogenetic aberrations in the gene are involved in cellular transformation and are associated with a variety of hematopoietic tumors, leukemias and lymphomas.

Artículo

Nirmatrelvir/Ritonavir and Subsequent PCR Negativity in Patients With B-Cell Lymphoma and Prolonged SARS-CoV-2 PCR Positivity: A Case Series.

Research record from EJHaem, 2026-10-24. PMID 42927348.

Artículo

Pitfalls in the diagnosis of diffuse large B-cell lymphoma with flow cytometry.

Research record from Acta Clin Belg, 2026-10-07. PMID 42841914.

Indicadores

TAG-72 Antigen

Tumor-associated oncofetal glycoprotein 72 (TAG-72) is a high molecular weight (220-400 kD) complex expressed by a wide variety of human adenocarcinomas. This antigen is expressed by a majority of invasive ductal breast carcinomas, and most colon, pancreatic, gastric, esophageal, lung (non-small cell), ovarian and endometrial adenocarcinomas, and on normal secretory endometrium, but not on other normal tissues. It is not expressed by leukemias, lymphomas, sarcomas, mesotheliomas, melanomas or benign tumors. The monoclonal antibodies against TAG-72 have been widely employed for the immunohistochemical analysis of adenocarcinomas as well as for radioimmunoscintigraphy and radioimmunoguided surgery.

Artículo

Utility of multiparametric flow cytometry in the diagnosis and staging of Classic Hodgkin lymphoma-Experience in real-world practice.

Research record from Cytometry B Clin Cytom, 2026-08-20. PMID 42622136.

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