Indicadores
EP300 Gene
This gene plays a role in DNA repair and regulation of transcription.
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Indicadores
This gene plays a role in DNA repair and regulation of transcription.
Indicadores
This gene may be involved in the mediation of DNA repair.
Indicadores
This gene may play a role in DNA cross-link repair.
Indicadores
This gene is involved in the regulation of meiosis, DNA repair and the cell cycle.
Indicadores
This gene plays a role in the regulation of both DNA repair and protein localization.
Indicadores
This gene may be involved in the regulation of DNA repair.
Indicadores
This gene is involved in both DNA binding and transcriptional regulation.
Indicadores
This gene plays a role in both DNA binding and transcriptional modulation.
Indicadores
This gene is involved in transcriptional regulation and plays a role in the mediation of DNA-protein interactions.
Indicadores
An antimetabolite and antifolate agent with antineoplastic and immunosuppressant activities. Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant activity although the mechanism(s) of actions is unclear.
Indicadores
This gene plays a role in DNA mismatch repair.
Indicadores
This gene plays a role in DNA mismatch repair mutations in the gene result in hereditary nonpolyposis colorectal cancer-1.