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Pruebas
The determination of the amount of SARS-related and/or MERS Coronavirus RNA which includes but not limited to SARS-CoV, SARS-CoV-2, other SARS-like Coronavirus, and/or MERS-CoV in a biological sample.
Artículo
Research record from J Gen Virol, 2026-10-01. PMID 42842305.
Glossary Term
A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
Pruebas
A determination of the number of transcript splice junctions based on nucleotide sequencing reads extending across the start and/or end of a junction.
Indicadores
An aminoglycoside antibiotic derived from Streptomyces tenebrarius with bacteriostatic activity. Following active transport into the cell, tobramycin binds irreversibly to a specific aminoglycoside receptor on the bacterial 30S ribosomal subunit and interferes with the initiation complex between messenger RNA and the 30S subunit, thereby inhibiting initiation of protein synthesis, consequently leading to bacterial cell death. In addition, tobramycin induces misreading of the mRNA template causing incorrect amino acids to be incorporated into the growing polypeptide chain, consequently interfering with protein elongation.
Pruebas
The determination of the amount of Toscana virus RNA in a sample.
Glossary Term
A genetic process in which single-stranded RNA with base sequence complementary to a region of plus strand DNA is synthesized by DNA-dependent RNA polymerases. Following the binding of RNA polymerase on DNA promoter regions, the RNA product is synthesized in a 5' to 3' direction, elongating RNA along the DNA strand as the polymerase proceeds, accompanied by unwinding and rewinding of the DNA template.
Glossary Term
The complete set of RNA transcripts that are produced by the genome, under specific circumstances or in a specific cell.
Glossary Term
A class of short adaptor RNAs that transfers a specific amino acid to a growing polypeptide chain at the ribosomal site of protein synthesis during translation. Each transfer RNA comprises a three-nucleotide sequence that is complementary to the triplet nucleotide coding sequence of an mRNA, conferring specificity to the amino acid being incorporated into the assembling protein.
Indicadores
This gene is involved in the splicing of mRNA.
Glossary Term
The product of so-called RNA genes; a functional RNA represents the final product of a gene rather than a transient molecule that will be translated into protein.
Indicadores
A branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.
