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Glossary Term
A purification method that binds nucleic acids to a silica membrane in a spin column through centrifugation or vacuum. It is a common manual and mid-throughput format with well-understood consumable logistics, but is less automation-friendly than magnetic bead approaches.
Glossary Term
A natural compound of silicon and oxygen found mostly in sand, Silica has three main crystalline varieties: quartz, tridymite, and cristobalite. Fine particulate silica dust from quartz rock causes over a long-term progressive lung injury, silicosis. (NCI04)
Pruebas
A measurement of the silver birch pollen IgE in a biological specimen.
Pruebas
A measurement of the silver birch pollen IgG4 in a biological specimen.
Glossary Term
A variation of a single nucleotide at a specific location of the genome due to base substitution, present at an appreciable frequency between individuals of a single interbreeding population.
Glossary Term
A variation of a single nucleotide at a specific location of the genome due to base substitution, which is found at any frequency in the population.
Glossary Term
A long linear single-stranded polymer formed from nucleotides attached to a deoxyribose backbone.
Indicadores
A natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production. (NCI04)
Pruebas
The determination of the amount of Sjogren's SS-A antibody present in a sample.
Indicadores
This gene plays a role in signal transduction and transcriptional activation. It is also involved in suppression of angiogenesis.
Glossary Term
A 20 to 25-nucleotide double-stranded RNA which is involved in a sequence-specific messenger RNA degradation process known as RNA interference.
Indicadores
This gene plays a role in chromatin remodeling, cell cycle control and regulation of transcription.
