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A heterotrimeric protein complex composed of complement component 8 (C8) chains alpha, beta and gamma. The alpha and gamma chains form a disulfide-linked dimer that is noncovalently associated with the beta chain. C8 inserts itself into target cell membranes following formation of the C5b-6-7 complex and then recruits 10-16 molecules of C9 to complete the formation of the membrane attack complex.

Indicadores

Complement Component C9

Complement component C9 (559 aa, ~63 kDa) is encoded by the human C9 gene. This protein plays a role in complement-mediated bacterial cell lysis.

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Clinical impact of plasma cell-free DNA metagenomic next-generation sequencing testing in neonatal and infant populations.

Clinical utility of CSF metagenomic next-generation sequencing in suspected CNS infection: performance against a composite reference standard and read-count stratification.

Clinical utility of metagenomic next-generation sequencing in the diagnosis of severe influenza complicated by invasive pulmonary aspergillosis.

Clinical Utility of Next-Generation Sequencing in Tumors Diagnosed as Lung Squamous Cell Carcinoma: Real-World Data of Diagnostic and Therapeutic Implications.

Clinical value of radial endobronchial ultrasound combined with metagenomic next-generation sequencing in the malignant tumors patients with pulmonary infection.

Clue Cell Count

Comparative diagnostic performance of metagenomic next-generation sequencing and conventional microbial culture in spinal infections: a systematic review and meta-analysis.

Comparative diagnostic performance of plasma microbial cell-free DNA sequencing versus amplicon-based blood next-generation sequencing in suspected bloodstream or endovascular infection: a single-center study.

Comparative evaluation of metagenomic and targeted next-generation sequencing for pathogen detection in bronchoalveolar lavage fluid from patients with lower respiratory tract infections: a retrospective cohort study.

Comparison of tissue acquisition techniques for Next-Generation Sequencing of non-small cell lung cancer (NSCLC).

Complement Component C8

Complement Component C9