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Article
Research record from Talanta, 2026-03-05. PMID 41812402.
Article
Research record from Clin Chim Acta, 2026-03-26. PMID 41903863.
Partner
PTS Diagnostics lists Highridge Pharmaceuticals in its distributor directory for Kenya.
Partner
Invivoscribe lists HISS DIAGNOSTICS GmbH in its distributor directory for Germany.
Glossary Term
Major protein component of chromatin. Highly conserved basic proteins, originally classified into classes based on the relative amounts of arginine and lysine in each protein. The various classes are now termed H1, H2A, H2B, H3, and H4. In chromatin, they are found in an octamer, containing two each of H2A, H2B, H3, and H4, complexed with DNA in nucleosomes. The histones in the octamer complex are also known as the core histones. The H1 class of histones, termed the linker histones, is loosely associated with the nucleosome.
Tests
The determination of the HIV viral load in a specimen using polymerase chain reaction.
Indicators
This gene plays a role in both DNA binding and transcriptional modulation.
Partner
TOYOBO lists Hölzel Diagnostika Handels GmbH in its distributor directory for Austria.
Glossary Term
The process of exchange of genetic material between autonomous replicons, which depends on regions of extensive sequence homology between the participating DNA strands. This process involves double-strand breakage of one participant, resection of the break, and strand invasion, followed by formation, displacement and resolution of the Holliday junction. This process is involved in repairing broken DNA and creating combinations of genes that may be unique from the parent duplexes. Disruptions in this process can result in inviability, premature aging and predisposition to cancers and degenerative diseases.
Partner
DiaSys lists HOSPIC SARL in its distributor directory for Algeria.
Tests
Detects high-risk human papillomavirus types used in cervical cancer screening.
Indicators
This gene plays a role in signal transduction and cellular communication.
