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Indicators
An antinuclear antibody directed against 52 or 60 kDa RNA-binding proteins in the nucleus. They can be associated with multiple autoimmune disorders, primarily Sjogren syndrome and system lupus erythematosus. Maternal anti-Ro antibody positivity can be associated with neonatal lupus.
Indicators
An antinuclear antibody directed against small nuclear ribonucleoproteins (snRNPs), that is highly specific, but has poor sensitivity for systemic lupus erythematosus (SLE). Presence of anti-Sm antibodies are associated with central nervous system, kidney, lung and cardiac involvement in SLE, but are not indicative of disease activity.
Glossary Term
A type of protein made by B lymphocytes in response to a foreign substance (antigen). Each antibody only binds to a specific antigen, helping to destroy the antigen directly or by assisting white blood cells to destroy the antigen.
Tests
Antibody serology tests look for specific antibodies in your blood. Antibodies are proteins your immune system makes to fight disease-causing germs (also called pathogens), such as viruses and bacteria .
Indicators
An autoantibody that reacts with cardiolipin. Different immunoglobulin subclasses and isotypes are associated with different diseases and conditions. Some anticardiolipin antibodies prolong phospholipid dependent clotting while others are associated with spontaneous abortion.
Glossary Term
Any substance, generally a protein, that stimulates the immune system and elicits an immune response. Recognition by the immune system elicits either a T-lymphocyte response, recognizing processed antigens, or a B-lymphocyte response, producing antibodies that bind to unprocessed antigens.
Tests
An ANCA test looks for antineutrophil cytoplasmic antibodies (ANCA) in a sample of your blood. Antibodies are proteins that your immune system makes to fight foreign substances, such as viruses and bacteria. ANCAs, however, are autoantibodies, which are antibodies that attack your own healthy tissues and organs by mistake. This can lead to the development of an autoimmune disease .
Partner
Invivoscribe lists ANTISEL A SELIDIS BROS S.A. in its distributor directory for Greece.
Partner
PTS Diagnostics lists Apex Biotechnology Corp. in its distributor directory for Taiwan China.
Partner
TOYOBO lists Apical Scientific Sdn. Bhd. in its distributor directory for Malaysia.
Partner
DiaSys lists Aquachim A.D. in its distributor directory for Bulgaria.
Indicators
This gene plays a role in the transcriptional activation of androgen responsive genes.
